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5 worst things you're doing to your gut

Keeping your gut bacteria happy may lead to better overall health.

Updated on September 9, 2024

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It’s estimated that about 39 trillion bacterial cells reside in the human body, the vast majority in the colon. Together with other microbes, these bacteria make up the gut microbiome.

Scientists know the microbiome aids in digestion and influences our immune and nervous systems. But they’re only beginning to understand the extent to which it affects our health overall.Show More

Woman with a cold drinking hot tea and taking cold medicine
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Not taking antibiotics as directed

Antibiotics treat bacterial infections. They can help you feel better quickly and can be life-saving. But antibiotics aren't finely targeted drugs, says Dr. Bridge. In the process of killing “bad” bacteria, they can end up killing a lot of the normal "helpful" bacteria that reside in our colon andShow More

woman holding remote and watching tv
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Not getting enough movement

Physical activity is likely good for your gut. For example, one 2020 review of studies in the Journal of the International Society of Sports Nutrition linked exercise to a greater number of good gut bacteria and a more diverse microbiome, among other benefits. Show More

Man smoking a cigarette
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Smoking

As if there weren’t enough reasons to kick the habit, studies suggest that smoking may also reduce the amount and diversity of beneficial gut flora, while increasing the number of harmful bacteria. There are several theories as to why. Smoking may:

  • Alter the pH balance in the gut, potentially
  • Show More
Stressed out businesswoman at work
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Not managing stress

It’s well known that stress can affect your digestive system. When you’re anxious, for example, you may develop diarrhea or become constipated. “That people get butterflies in their stomach when they’re nervous is a real effect,” says Bridge. Some early studies indicate stress may stifle theShow More

Pizza, fries and burger
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Eating an unhealthy diet

Diet is intimately connected to gut health, and many experts believe eating plans that go heavy on saturated fats, added simple sugars, and processed foods—and light on natural fiber—do a number on gastrointestinal flora. For example, several studies on both humans and mice suggest that high-fatShow More

Slideshow sources open slideshow sources

Sender R, Fuchs S, & Milo R. Revised Estimates for the Number of Human and Bacteria Cells in the Body. PLoS Biology. August 2016. 14(8), e1002533.
Abbott A. Scientists bust myth that our bodies have more bacteria than human cells. Nature. 08 January 2016.
U.S. Department of Veterans Affairs. How a Healthy Gut Makes for a Healthier You. June 5, 2017. Accessed May 2, 2022.
Foster JA, Rinaman L, & Cryan JF. Stress & the gut-brain axis: Regulation by the microbiome. Neurobiology of Stress. December 2017, 7, 124–136.
Singh RK, Chang HW, et al. Influence of diet on the gut microbiome and implications for human health. Journal of Translational Medicine. 2017; 15: 73.
Harvard Health Publishing. Can gut bacteria improve your health? October 2016. Accessed May 2, 2022.
Langdon A, Crook N, & Dantas G. The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation. Genome Medicine. 2016; 8(1), 39.
Mohr AE, Jäger R., et al. The athletic gut microbiota. Journal of the International Society of Sports Nutrition. 2020. 17(1), 24.
Mach N & Fuster-Botella D. Endurance exercise and gut microbiota: A review. Journal of Sport and Health Science. June 2017. Volume 6, Issue 2, Pages 179-197.
Douglas Main. Rugby Player Study Suggests Exercise Diversifies Gut Bacteria. Popular Science. June 11, 2014. 
Monda V, Villano I, et a. Exercise Modifies the Gut Microbiota with Positive Health Effects. Oxidative Medicine and Cellular Longevity. 2017, 3831972.
Savin Z, Kivity S, et al. Smoking and the intestinal microbiome. Archives of Microbiology. 2018 Jul;200(5):677-684. 
Lee SH. Intestinal permeability regulation by tight junction: implication on inflammatory bowel diseases. Intestinal Research. January 2015. 13(1), 11–18.
GI Society. The Effects of Smoking on Inflammatory Bowel Disease. 2015. Accessed May 2, 2022.
American Psychological Association. That gut feeling. September 2012. Accessed May 2, 2022.
Saulnier DM, Ringel Y, et al. The intestinal microbiome, probiotics and prebiotics in neurogastroenterology. Gut Microbes. January 2013. 4(1), 17–27.
Holscher HD. Dietary fiber and prebiotics and the gastrointestinal microbiota. Gut Microbes. 2017; 8(2), 172–184.
Sawicki CM, Livingston KA. et al. Dietary Fiber and the Human Gut Microbiota: Application of Evidence Mapping Methodology. Nutrients. February 2017; 9(2), 125.
Costantini L, Molinari R, et al. Impact of Omega-3 Fatty Acids on the Gut Microbiota. International Journal of Molecular Sciences. December 2017; 18(12), 2645.

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