Never use insulin if it looks abnormal. Regular, lispro, aspart, and glargine insulins are clear. If you use clear insulin, always check for any floating particles, cloudiness, or change in color. This could be a sign that your insulin is contaminated or has lost its strength.
Other types of insulin come as suspensions. This means that the material is not completely dissolved, and you might be able to see solid material floating in liquid. However, it should look uniformly cloudy. If you are using NPH, check that your insulin is free of any large clumps of material. Do not use any insulin if you see chunks of material floating around. These changes could mean that crystals or aggregates are forming and the insulin is spoiled or denatured. This can be caused by too much shaking of the insulin bottle or storing insulin at temperatures that are either too hot or too cold.
If you have been instructed to dilute your insulin, use only the diluent recommended by the manufacturer. Properly diluted insulin is good for 2 to 6 weeks stored in the refrigerator. If you find anything wrong with your insulin right after you buy it, return it immediately. If the condition develops later, try to figure out whether you have handled or stored the insulin the wrong way. If not, talk to your pharmacist about a refund or exchange.
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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.