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What are the side effects of normal saline?

Stacy Wiegman, PharmD
Stacy Wiegman, PharmD
Pharmacy
answer
Receiving normal saline can lead to fluid overload and excessive levels of sodium in the blood. Normal saline for injection can cause inflammation or irritation at the injection site. Rare side effects of this solution related to receiving too much volume include: diarrhea; cramps; nausea; vomiting; increases in heart rate, thirst, sweating, saliva, urine or tears; dizziness or lightheadedness; sleepiness; restlessness or irritability; swelling in the extremities; headaches; muscle twitching, convulsions or rigidness; or difficulty breathing.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.