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Tongue spasms have a number of possible causes. Sometimes it's caused by a disorder such as cerebral palsy or multiple sclerosis or by nerve damage from a stroke. Movement disorders such as dystonia or Meige's syndrome, which cause involuntary muscle contractions and spasms, can also cause tongue spasms. Sometimes a tongue spasm is a side effect of certain antipsychotic drugs. The drug phochlorperazine (Compazine), which is used as an antipsychotic and also to treat severe nausea and vomiting, can cause tongue spasms.
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