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If you are taking vitamin B3 on a regular basis, try to take it at the same time every day -- preferably with meals -- and at least eight ounces of cool water according to your doctor's or the label's instructions. Taking a nonsteroidal anti-inflammatory like aspirin one half hour before taking B3 may reduce side effects of skin irritation and flushing. Do not take B3 with hot liquids, or you will probably experience more side effects. If you take the extended-release tablet before going to bed, take it with a snack and at least eight ounces of cool water. Be sure to swallow it without chewing, and do not break it beforehand.
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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.