How sugar affects rheumatoid arthritis

Evidence suggests consuming too much sugar may raise RA risk or worsen existing symptoms.

pouring soda from a can into a glass

Updated on January 13, 2025.

Rheumatoid arthritis (RA) is a condition that causes joints to become painful, swollen, and stiff. Experts aren’t exactly sure what causes RA. Many believe it’s some mix of genetics, environment, and hormones. 

Some research, however, suggests that consuming too much sugar may also play a role. It may increase your risk of developing RA, and if you already have the condition, it could worsen your symptoms.

How sugar may affect RA

There are a number of different ways sugar could influence RA.

Inflammation

There’s good evidence extra sugar intake contributes to inflammation. Chronic inflammation raises the risk of developing RA. It can also aggravate joint pain tenderness and discomfort—common issues for people with RA.

Weight gain

Too much sugar can contribute to weight gain, and being overweight or obese is an RA risk factor. This is partly because extra fat tissue can contribute to inflammation. Carrying excess pounds can also place further pressure on joints, worsening pain.

Gut microbiome changes

Your gut microbiome is the collection of bacteria that live in your digestive system. These microbes help your body process food, but also influence the immune system. Excess sugar intake can alter the microbiome, leading to inflammation and reducing the amount of beneficial organisms present in your gut. These may influence RA development.

Additional health risks

Consuming too much sugar is linked to a higher risk of developing certain chronic diseases, including diabetes and heart disease. People with RA are already at a higher risk for many of these conditions. Having RA along with additional illnesses can lead to more pain, complicate treatment, and add to other problems, including poor sleep and mental health difficulties.

Ways to cut back on sugar

Watching your sugar intake may improve RA risk and symptoms and can make a significant difference your overall health. Try taking these steps to reduce the amount you eat.

Read labels

Much of the excess sugar in the average Western diet comes from processed foods, including candy, cereal, and baked goods. When you shop for groceries, be sure to read nutrition labels. Look especially for added sugar content, which will be listed in grams and as a Daily Value (DV) percentage. No more than 10 percent of your daily calories should come from added sugars. That’s about 50 grams each day, based on a 2,000-calorie daily diet.

Switch your beverages

Soft drinks are another major source of added sugars. These include soda, sports drinks, energy drinks, and even fruit juices. To cut back, try slowly replacing them with low-sugar or sugar-free options. Seltzer, unsweetened iced tea, and water are popular choices.

Stir in cinnamon

Herbs, spices, vinegars, citrus, and extracts can bring flavor to many dishes without adding extra sugar. Try a cinnamon stick in your tea, vanilla extract in your yogurt, or a squeeze of lemon in your water.

Make your own pasta sauce

Ready-made pasta sauce is often more sugary than you might expect. Look for low-sugar varieties or make your own at home using crushed, canned tomatoes and a handful of your favorite herbs. It takes just minutes and runs a fraction of the cost of jarred sauces.

Article sources open article sources

Cleveland Clinic. Rheumatoid Arthritis. November 6, 2024.
Ma X, Nan F, Liang H, Shu P, et al. Excessive intake of sugar: An accomplice of inflammation. Front Immunol. 2022 Aug 31;13:988481.
Hu Y, Costenbader KH, Gao X, Al-Daabil M, et al. Sugar-sweetened soda consumption and risk of developing rheumatoid arthritis in women. Am J Clin Nutr. 2014 Sep;100(3):959-67. 
Della Corte KW, Perrar I, Penczynski KJ, Schwingshackl L, et al. Effect of Dietary Sugar Intake on Biomarkers of Subclinical Inflammation: A Systematic Review and Meta-Analysis of Intervention Studies. Nutrients. 2018 May 12;10(5):606.
Arthritis Foundation. How Fat Affects Rheumatoid Arthritis. Accessed January 9, 2025.
UCLA Health. Increased sugar intake may have triggered RA flare. February 8, 2023.
Marchand NE, Sparks JA, Malspeis S, Yoshida K, et al. Long-term weight changes and risk of rheumatoid arthritis among women in a prospective cohort: a marginal structural model approach. Rheumatology (Oxford). 2022 Apr 11;61(4):1430-1439.
Ohno T, Aune D, Heath AK. Adiposity and the risk of rheumatoid arthritis: a systematic review and meta-analysis of cohort studies. Sci Rep. 2020 Sep 29;10(1):16006. 
Arthritis Foundation. Comorbid Conditions in Inflammatory Arthritis. Accessed January 9, 2025.
U.S. Food & Drug Administration. Added Sugars on the Nutrition Facts Label. March 5, 2024.
USDA. Dietary Guidelines for Americans 2020-2025. December 2020.
Harvard TH Chan School of Public Health. Sugary Drinks. August 2023.

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