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4 common bipolar triggers and how to manage them

Life events and habits can make bipolar episodes worse, or even prompt a relapse.

Updated on October 22, 2024

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About 8 million adults in the United States have bipolar disorder, a condition that causes changes in mood that are disruptive to everyday life. Nearly 83 percent of people with bipolar have a severe case, which means they report experiencing serious impairments to their work, social life, or family life. Bipolar disorder affects men and women equally. While it canShow More

The face of a person with bipolar disorder mixed in with an image of billowing clouds
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Mood changes and bipolar episodes

Most people experience sadness, sleeplessness, and lack of concentration during their lifetimes. But people with bipolar disorder experience these moods with greater intensity and in cycles. There are three different types of mood episodes associated with bipolar disorder. These include:

A person with bipolar disorder discusses their condition with a therapist
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Understanding the types of bipolar disorder

In addition to the various episode types, there are different types of bipolar disorder. The three major types are:

  • Bipolar I disorder is when a person has at least one severe manic episode. Having a depressive episode is also common with bipolar I.
  • Bipolar II disorder is when a person
  • Show More
Young person stressed at work and holding their head in their hands at a desk
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Stress

In general, people with bipolar disorder have a harder time managing stress than people without the condition. They may have difficulty coping with situations and may interpret otherwise insignificant events as stressful. High stress levels can cause depressive, manic, or hypomanic episodes, asShow More

A depressed person laying in bed, unable to start their day
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Lack of sleep

A significant change in sleep patterns is a symptom of bipolar disorder. Changes to your sleep-wake cycle, or circadian rhythm, can also trigger a bipolar episode, according to a 2023 systematic review published in the Journal of Psychiatric Research. For those with bipolar disorder, shiftShow More

Various illicit drugs
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Drug use

It’s difficult to pinpoint exact numbers, but population surveys have shown that approximately 50 percent of people with bipolar type 1 also have either substance or alcohol use disorder.

In many cases, those with bipolar disorder may use drugs or alcohol to try and ease symptoms like anxiety, pain,Show More

A lone glass of bourbon with ice on a wooden table
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Alcohol use

Alcohol depresses the central nervous system and contributes to depressive symptoms. Because alcohol alters a person’s awareness and inhibition, it’s especially dangerous for people with bipolar disorder. And people with bipolar disorder who also have alcohol use disorder will usually experienceShow More

Someone stubbing out a cigarrette
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Nicotine use

Smoking is unhealthy for everyone, because it causes cancer and raises the risk for heart disease and other serious health conditions. Nicotine dependence (being addicted to smoking) is also linked to more severe experiences of psychosis in people with bipolar I. People with bipolar who smoke areShow More

A pregnant person with bipolar disorder holding their belly and thinking in front of a window
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Pregnancy and childbirth

According to a 2024 review and meta-analysis published in the Journal of Clinical Psychiatry, about 2.6 percent of pregnant people who have not been previously diagnosed with a psychiatric illness will develop bipolar disorder while pregnant. In those who had a bipolar diagnosis before gettingShow More

A pregnant person having a conversation with their doctor about bipolar triggers
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Treating bipolar during pregnancy

In general, it can be difficult to weigh the risk and benefits when it comes to treating mental illness during pregnancy. That’s why it’s important to talk with an obstetrician/gynecologist (OBGYN) and mental health professional to determine the right treatment plan. Common bipolar medicationsShow More

Slideshow sources open slideshow sources

Nierenberg AA, Agustini B, Köhler-Forsberg O, et al. Diagnosis and Treatment of Bipolar Disorder: A Review. JAMA. 2023 Oct 10;330(14):1370-1380. 
National Institute of Mental Health. Bipolar Disorder. Page accessed June 24, 2024.
Harm Research Institute. Sheehan Disability Scale (SDS). Page accessed June 24, 2024.
National Alliance on Mental Illness. Bipolar Disorder. Page accessed June 24, 2024.
Mayo Clinic. Bipolar Disorder. Page last reviewed December 13, 2022.
American Psychiatric Association (2022). Bipolar and related disorders. In Diagnostic and statistical manual of mental disorders (5th ed., text rev.).
Umeoka EHL, van Leeuwen JMC, Vinkers CH, et al. The Role of Stress in Bipolar Disorder. Curr Top Behav Neurosci. 2021;48:21-39. 
International Bipolar Foundation. Getting a Handle on Stress When You Have Bipolar Disorder, Part 2: The Connection Between Stress and Bipolar Disorder. Page accessed June 24, 2024.
Rodrigues Cordeiro C, Côrte-Real BR, Saraiva R, et al. Triggers for acute mood episodes in bipolar disorder: A systematic review. J Psychiatr Res. 2023 May;161:237-260.
Ramirez-Mahaluf JP, Rozas-Serri E, Ivanovic-Zuvic F, et al. Effectiveness of Sleep Deprivation in Treating Acute Bipolar Depression as Augmentation Strategy: A Systematic Review and Meta-Analysis. Front Psychiatry. 2020 Feb 25;11:70.
Centers for Disease Control and Prevention. About Sleep. Page accessed October 21, 2024.
Preuss UW, Schaefer M, Born C, et al. Bipolar Disorder and Comorbid Use of Illicit Substances. Medicina (Kaunas). 2021 Nov 17;57(11):1256. 
Kung, Simon. “Is there a connection between bipolar disorder and alcohol use disorder?” Mayo Clinic. February 13, 2024.
Kuhns L, Kroon E, Colyer-Patel K, et al. Associations between cannabis use, cannabis use disorder, and mood disorders: longitudinal, genetic, and neurocognitive evidence. Psychopharmacology (Berl). 2022 May;239(5):1231-1249.
van Draanen J, Tsang C, Mitra S, et al. Mental disorder and opioid overdose: a systematic review. Soc Psychiatry Psychiatr Epidemiol. 2022 Apr;57(4):647-671.
Morton E, Sakai K, Ashtari A, et al. Risks and benefits of psilocybin use in people with bipolar disorder: An international web-based survey on experiences of 'magic mushroom' consumption. J Psychopharmacol. 2023 Jan;37(1):49-60.
Grunze H, Schaefer M, Scherk H, et al. Comorbid Bipolar and Alcohol Use Disorder-A Therapeutic Challenge. Front Psychiatry. 2021 Mar 23;12:660432.
Drugs.com. Bipolar Medications and Alcohol Interactions. May 30, 2024.
Grunze A, Mosolov S, Grunze H, et al. The detrimental effects of smoking on the course and outcome in adults with bipolar disorder-A narrative review. Front Psychiatry. 2023 Jan 9;13:1114432.
Masters GA, Hugunin J, Xu L, et al. Prevalence of Bipolar Disorder in Perinatal Women: A Systematic Review and Meta-Analysis. J Clin Psychiatry. 2022 Jul 13;83(5):21r14045.
Singh S, Deep R. Pharmacological treatment of bipolar disorder in pregnancy: An update on safety considerations. Indian J Pharmacol. 2022 Nov-Dec;54(6):443-451. 

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