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How is the immune system involved with atopic dermatitis?

Updated on October 23, 2024

People with atopic dermatitis often have a sensitive immune system.

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Transcript

00:00
I have a question. I heard that the immune system is involved with eczema. Is that true? And also, how does that work?
00:09
Thanks so much for asking this question. It's a good one. Essentially, people with Atopic Dermatitis, or AD,
00:16
often have a sensitive immune system. Now, your immune system is what fights off the things that make you sick.
00:24
It's activated when your body senses something that doesn't belong. We call these intruders antigens.
00:31
Normally, your skin does a pretty good job of keeping antigens out. But with AD, the skin barrier isn't working as it should,
00:40
and that allows them to slip through. The immune system then senses that something is wrong,
00:46
and it responds by releasing a whole bunch of cells to kill these foreign substances. You can see these cells in yellow.
00:54
This immune response produces inflammation in the affected area, and that inflammation is what
01:01
causes the painful symptoms of atopic dermatitis. It's a complicated process, and each individual
01:10
is affected by AD differently. Talk to your dermatologist to develop a plan that can

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